Welcome to the fifth season of the ISTAART PIA Relay Podcast, brought to you by Dementia Researcher. In this six-part series, members of ISTAART professional interest areas (PIAs) take turns interviewing their colleagues about the latest research in Alzheimer's disease and other dementias. This episode features a Caitlyn Fastenau, a PhD candidate from the University of Texas Health Science Centre interviewing Dr Jessica Caldwell, a neuropsychologist and director of the Women’s Alzheimer’s Movement Prevention and Research Centre at Cleveland Clinic. Dr Caldwell discusses her pioneering work at the world's only clinic designed specifically for women to reduce their Alzheimer's risk, focusing on sex and gender differences in the disease. She highlights the critical role of menopause, stress, and hormonal changes in Alzheimer's risk and shares insights into the importance of diverse research populations and the unique challenges faced by women caregivers. Tune-in as explore hot topics of sex and gender differences in Alzheimer's research, including the impact of menopause, the need for gender-diverse studies, and the initiatives of the ISTAART Sex and Gender PIA and what they have planned for AAIC. Whether you're a researcher, clinician, or someone affected by Alzheimer's, this episode offers valuable perspectives on the intersections of gender, health, and dementia. -- The Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) convenes the global Alzheimer’s and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer’s and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests. -- There are currently 30 PIAs covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between. To sign-up to ISTAART and a PIA visit: http://www.istaart.alz.org Note: ISTAART Membership is free for students worldwide, and for researchers of all levels based in Low- and Middle-Income Countries. -- To book your place at this year’s AAIC (In-person and online) visit: http://www.aaic.alz.org You can also enjoy this show as a video on our YouTube Channel at: https://youtu.be/E0NWtCyJtzI -- Find more information on our guests, and a full transcript of this podcast on our website at: www.dementiaresearcher.nihr.ac.uk/podcast -- The views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association.